According to the news of Radio-France, a fire broke out in the 5-storey building in the city of Grasse at dawn.
In the incident, 3 people lost their lives and 21 people were injured, 3 of them seriously.
The fire, in which nearly 50 firefighters came to the region and intervened with 17 vehicles, was brought under control.
The building where the fire broke out and the surrounding structures were evacuated as a precaution.
An investigation has been launched into the fire, the cause of which has not yet been clarified.
In the city of Colmar in the Alsace region, 11 people who were trapped in the fire that broke out in the summer residence where the disabled and their companions were staying, lost their lives on 9 August.